Structure of Apoptosis-Linked Protein ALG-2
نویسندگان
چکیده
منابع مشابه
Two forms of the apoptosis-linked protein ALG-2 with different Ca(2+) affinities and target recognition.
The apoptosis-linked gene ALG-2 encodes a Ca(2+)-binding protein of the penta EF-hand family. To investigate the Ca(2+) binding properties of the recombinant ALG-2 protein, we have cloned ALG-2 cDNA from mouse liver mRNA. Sequence analysis showed that two types of clones were present. One (named ALG-2,5) corresponds to the published ALG-2 sequence (Vito, P., Lacana, E., and D'Adamio, L. (1996) ...
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By yeast two-hybrid screening using the calcium-binding protein ALG-2 as bait a new target of ALG-2 was identified, the RNA-binding protein RBM22. In order to confirm these interactions in vivo we prepared fluorescent constructs by using the monomeric red fluorescent protein to label ALG-2 and the enhanced green fluorescent protein to label RBM22. Confocal microscopy of NIH 3T3 cells transfecte...
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ژورنال
عنوان ژورنال: Structure
سال: 2001
ISSN: 0969-2126
DOI: 10.1016/s0969-2126(01)00585-8